Rosa26 Locus Supports Tissue-Specific Promoter Driving Transgene Expression Specifically in Pig
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چکیده
منابع مشابه
Rosa26 Locus Supports Tissue-Specific Promoter Driving Transgene Expression Specifically in Pig
Genetically modified pigs have become a popular model system in fundamental research, agricultural and biomedical applications. However, random integration often result in unstable expression of transgene and unpredictable phenotypes. The Rosa26 locus has been widely used to produce genetic modified animals with high and consistent expressing of transgene in mouse, human and rat, as it can be t...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0107945